Buying Guide

The Best Ergonomic Wireless Mouse

Five mice compared, from the Lenovo WL310 to the MX Vertical, with the trade-offs of each named.

By , PC Hardware Editor

12 min read5 products evaluated

A desk setup with a keyboard, mouse and headset beside a monitor
Illustrative image

An ergonomic wireless mouse changes the grip, with a vertical handshake, a thumb trackball or a sculpted shape, and removes the cable drag. These are ordered by listed battery life.

Our comparison rests on published figures for battery life, sensor and grip; where a maker leaves out battery life, we say so, and no figure here comes from our own testing.

Quick Picks

Which of the 5 picks to look at first. Tap a name for the full analysis.

  1. Also Consider

    Logitech M720 Triathlon Multi-Device Mouse

    Switching between 3 computers at the touch of a button.

    Best for: Buyers who want switching between 3 computers at the touch of a button.

    Check price for Logitech M720 Triathlon Multi-Device Mouse on Amazon (opens in a new tab)
  2. Strong Alternative

    Logitech Signature M650

    Customizable side buttons.

    Best for: Buyers who want customizable side buttons.

    Check price for Logitech Signature M650 on Amazon (opens in a new tab)
  3. Lowest Price Here

    Lenovo WL310 Bluetooth Silent Mouse

    A lower price than the M720 and the rest when we checked.

    Best for: Buyers who would rather put the savings elsewhere than into the M720.

    Check price for Lenovo WL310 Bluetooth Silent Mouse on Amazon (opens in a new tab)
  4. Worth a Look

    Logitech Lift Vertical

    Whisper-quiet clicks.

    Best for: Buyers who want whisper-quiet clicks.

    Check price for Logitech Lift Vertical on Amazon (opens in a new tab)
  5. Highest-Resolution Sensor

    Logitech MX Vertical Wireless Ergonomic Mouse

    The highest sensor resolution here (4,000 DPI).

    Best for: Users who move the cursor across very wide desktops.

    Check price for Logitech MX Vertical Wireless Ergonomic Mouse on Amazon (opens in a new tab)

Our Picks

Also Consider1 of 5

Logitech M720 Triathlon Multi-Device Mouse

Logitech's M720 Triathlon switches between three computers with a button and supports Logitech Flow.

Best for

Buyers who want switching between 3 computers at the touch of a button.

Skip if

Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Logitech M720 Triathlon Multi-Device Mouse

Why we like it

It has 24 months of battery life. Its hyper-fast scroll wheel spins freely through long documents and switches back to click-by-click scrolling when you need precision. The rubber body and sculpted right-hand shape suit a relaxed palm grip.

Logitech Flow moves the cursor, text and files between up to three computers, and it connects over Bluetooth or the Unifying receiver. The Unifying receiver can also pair up to six compatible Logitech devices, which saves USB ports. When we checked, only the Lenovo WL310 cost less, and the Signature M650 cost more. If you want a confirmed sensor resolution, look to the MX Vertical instead: it offers 4,000 DPI, while this one gives no figure.

Key specs

Battery life
up to 24 months
Programmable buttons
6
Grip
Full-size, right-handed
Connection
Bluetooth or Unifying receiver, 3 devices

Pros

  • Switching between 3 computers at the touch of a button
  • Logitech Flow across computers
  • Unifying receiver for up to 6 Logitech devices

Cons

  • Costs more than the Lenovo WL310 at the time of writing

Strong Alternative2 of 5

Logitech Signature M650

Logitech's Signature M650 is a quiet-click mouse sized for small to medium hands.

Best for

Buyers who want customizable side buttons.

Skip if

Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Logitech Signature M650

Why we like it

It supports Windows, macOS, Linux, ChromeOS, iPadOS and Android. Its SmartWheel switches between line-by-line and fast scrolling, and rubber grips suit small to medium hands. Plastics include up to 64% recycled material.

It shares a bluetooth or Logi Bolt connection with the Lift; the Lenovo WL310 goes with a bluetooth 5.0 connection. It also offers customizable side buttons and silent clicks. It is shaped for right hands only.

It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. When we checked, only the M720 and cheaper picks cost less, and the Lift cost more. If you want a confirmed sensor resolution, look to the MX Vertical instead: it offers 4,000 DPI, while this one gives no figure.

Key specs

Battery life
up to 24 months
Grip
Right-handed, small to medium hands
Connection
Bluetooth or Logi Bolt

Pros

  • Customizable side buttons
  • Silent clicks
  • Support for Windows, macOS, Linux, ChromeOS, iPadOS and Android

Cons

  • Costs more than the Lenovo WL310 at the time of writing

Lowest Price Here3 of 5

Lenovo WL310 Bluetooth Silent Mouse

Lenovo's WL310 is a silent Bluetooth mouse with 1000, 1200 and 1600 DPI steps.

Best for

Buyers who would rather put the savings elsewhere than into the M720.

Skip if

Choose another pick if you can't accept this: sensor resolution of 1,600 DPI, behind the MX Vertical (4,000 DPI).
Lenovo WL310 Bluetooth Silent Mouse

Why we like it

It needs no receiver. Its clicks are near silent, which suits shared rooms and late sessions. DPI switches between 1,000, 1,200 and 1,600.

You get a bluetooth 5.0 connection here, which sets it apart from the Lift and its a bluetooth or Logi Bolt connection. Another plus: ergonomic grip, the only one here. It makes the most sense for buyers who would rather put the savings elsewhere than into the M720, since it offers a lower price than the M720 and the rest when we checked.

It cost the least of the 5 picks at the time of writing, with the M720 the next step up. There is no published battery life figure, whereas the M720 runs for up to 24 months.

Key specs

Sensor
1,600 DPI
Grip
Ergonomic
Connection
Bluetooth 5.0

Pros

  • Silent clicks
  • 1000, 1200 and 1600 DPI steps
  • No USB receiver needed
  • Ergonomic grip, the only one here

Cons

  • Sensor resolution of 1,600 DPI, behind the MX Vertical (4,000 DPI)

Worth a Look4 of 5

Logitech Lift Vertical

Lift is Logitech's vertical mouse for small to medium right hands, holding the wrist at 57 degrees to reduce forearm twist.

Best for

Buyers who want whisper-quiet clicks.

Skip if

If budget leads, the Lenovo WL310 was cheaper at our last price check.
Logitech Lift Vertical

Why we like it

It adds whisper-quiet clicks and a SmartWheel, and connects over Bluetooth or Logi Bolt. Logitech sizes it for small to medium right hands, with a 57-degree angle and a padded thumb rest. The soft-textured grip suits all-day office use.

The plastic parts include certified post-consumer recycled plastic, and it works with Windows, macOS, iPadOS, Chrome OS and Linux. It shares a bluetooth or Logi Bolt connection with the Signature M650; the Lenovo WL310 goes with a bluetooth 5.0 connection. You also get certification by leading ergonomists.

Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. When we checked, only the Signature M650 and cheaper picks cost less, and the MX Vertical cost more.

Key specs

Grip
57-degree vertical, right-handed, small to medium hands
Connection
Bluetooth or Logi Bolt

Pros

  • Whisper-quiet clicks
  • Certification by leading ergonomists
  • Bluetooth or Logi Bolt connection

Cons

  • Costs more than the Lenovo WL310 at the time of writing

The catch

If you want a confirmed battery life, look to the M720 instead: it runs for up to 24 months, while this one gives no figure.

Highest-Resolution Sensor5 of 5

Logitech MX Vertical Wireless Ergonomic Mouse

Logitech's MX Vertical sets the hand at 57 degrees with a thumb rest and a textured rubber surface.

Best for

Users who move the cursor across very wide desktops.

Skip if

Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Logitech MX Vertical Wireless Ergonomic Mouse

Why we like it

A cursor speed switch changes sensitivity with one press, and Logitech says the shape fits a variety of hand sizes. Its 57-degree angle puts your hand in a handshake position, which Logitech says reduces muscle activity by 10%. The design was tested against criteria from ergonomists.

Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It is shaped for right hands only. Only the Lift came close to it on price at the time of writing; it cost the most of the 5 picks. There is no published battery life figure, whereas the M720 runs for up to 24 months.

Key specs

Sensor
4,000 DPI
Grip
Vertical, right-handed (57°)
Connection
Wireless, USB receiver

Pros

  • 57-degree vertical angle with a thumb rest
  • Cursor speed switch that changes DPI with one button
  • Textured rubber surface
  • Highest sensor resolution of the picks (4,000 DPI)

Cons

  • Costs more than the Lenovo WL310 at the time of writing

How We Chose

Alex Morgan compared the manufacturer specifications, connectivity, warranty terms and compatibility of every pick. Figures come from the makers unless a third-party source is named; we did not test these products ourselves.

A hand on a white gaming mouse, and the same mouse shown from below
A hand on a white gaming mouse, and the same mouse shown from below
How these picks were ranked
We lined up five mice on battery life, sensor resolution, grip and connection, using each maker's published specs. These are research figures, not bench results: 3 of 5 picks leave out battery life.
The shared baseline
All 5, from the M720 to the MX Vertical, state grip and connection.
Where the specs have gaps
The Lenovo WL310, the Lift and the MX Vertical give no battery life; the M720, the Signature M650 and the Lift give no sensor resolution.
Price range
At our last check the picks ran from the Lenovo WL310 (under $50) to the MX Vertical ($50 to $100).

What to Look for in an Ergonomic Wireless Mouse

Key buying criteria so you get the right fit the first time.

  1. Sensor resolution across these picks

    Here sensor resolution runs from 1,600 DPI on the Lenovo WL310 to 4,000 DPI on the MX Vertical, a 150% spread. Start with the MX Vertical if sensor resolution decides it. The M720, the Signature M650 and the Lift give no sensor resolution figure, so 2 of 5 picks are compared here.

  2. Features beyond the spec table

    The Lenovo WL310: 1000, 1200 and 1600 DPI steps. The Lift: certification by leading ergonomists. The MX Vertical: a cursor speed switch that changes DPI with one button.

    A hand next to a black wireless mouse on a blue mousepad
    A hand next to a black wireless mouse on a blue mousepad
  3. Budget

    Under $50 buys the Lenovo WL310, the M720 and the Signature M650; $50 to $100 buys the Lift and the MX Vertical at our last check.

  4. Match the pick to your priority

    Buyers who would rather put the savings elsewhere than into the M720: the Lenovo WL310. Users who move the cursor across very wide desktops: the MX Vertical.

    A hand holding a light-blue mouse on a red mousepad
    A hand holding a light-blue mouse on a red mousepad
  5. Quiet clicks for shared rooms

    Silent or quiet-click switches reduce noise on calls and in shared offices. The feel is slightly softer.

How to Choose an Ergonomic Wireless Mouse

By priority

PriorityConsiderWhy
Buyers who want switching between 3 computers at the touch of a buttonM720Switching between 3 computers at the touch of a button
Buyers who want customizable side buttonsSignature M650Customizable side buttons
Buyers who would rather put the savings elsewhere than into the M720Lenovo WL310A lower price than the M720 and the rest when we checked
Buyers who want whisper-quiet clicksLiftWhisper-quiet clicks
Users who move the cursor across very wide desktopsMX VerticalThe highest sensor resolution here (4,000 DPI)

Scroll sideways to see every column.

Key specs side by side

The MX Vertical leads on sensor resolution at 4,000 DPI, ahead of the Lenovo WL310 at 1,600 DPI. "Not listed" marks battery life where the Lenovo WL310, the Lift and the MX Vertical leave the figure out.

MiceBattery lifeSensorGripConnection
M720up to 24 monthsNot listedFull-size, right-handedBluetooth or Unifying receiver, 3 devices
Signature M650up to 24 monthsNot listedRight-handed, small to medium handsBluetooth or Logi Bolt
Lenovo WL310Not listed1,600 DPIErgonomicBluetooth 5.0
LiftNot listedNot listed57-degree vertical, right-handed, small to medium handsBluetooth or Logi Bolt
MX VerticalNot listed4,000 DPIVertical, right-handed (57°)Wireless, USB receiver

Scroll sideways to see every column.

By price at the time of writing

At our last check the cheapest pick, the Lenovo WL310, sat in the under $50 tier, 2 tiers in all up to the MX Vertical at $50 to $100; Amazon prices move, so recheck before buying.

Price tierMice
Under $50Lenovo WL310, M720, Signature M650
About $50 to $100Lift, MX Vertical

Frequently Asked Questions

How does the Lenovo WL310 compare with the MX Vertical on sensor resolution?

Between the top two, it is 4,000 DPI on the MX Vertical against 1,600 DPI on the Lenovo WL310, a 150% difference. No sensor resolution figure is published for the M720, the Signature M650 and the Lift, which leaves 2 of 5 picks ranked here.

Is the MX Vertical worth paying more than the Lenovo WL310?

On paper it adds sensor resolution (4,000 DPI against 1,600 DPI). The Lenovo WL310 sat in the under $50 tier and the MX Vertical in the $50 to $100 tier when we checked, with 3 other picks between them; pay the difference only if sensor resolution decides your purchase.

What makes the MX Vertical the Highest-Resolution Sensor?

The label rests on the highest sensor resolution here (4,000 DPI). The Lenovo WL310 is next on sensor resolution at 1,600 DPI, so this pick's 4,000 DPI is 150% further out. The Lenovo WL310, the cheapest pick, sat in the under $50 tier against $50 to $100 here, without out-ranking it on any listed spec. It is aimed at anyone who moves the cursor across very wide desktops.

Beyond the specs, what sets the M720 and the Signature M650 apart?

The M720: switching between 3 computers at the touch of a button. The Signature M650: customizable side buttons. The Lenovo WL310: silent clicks.

Should I pick the M720 or the MX Vertical?

The M720 suits buyers who want switching between 3 computers at the touch of a button; the MX Vertical suits users who move the cursor across very wide desktops.

Bottom Line

Our first pick is the M720, chosen for switching between 3 computers at the touch of a button. Look at the Signature M650 for customizable side buttons, the Lenovo WL310 for a lower price than the M720 and the rest when we checked and the Lift for whisper-quiet clicks if those matter more to you.

Any new grip takes a week or so to adjust to; give it time before judging.

About the author

PC Hardware Editor

Alex covers PC hardware, monitors, components, upgrades and peripherals for The PC Journal, with a focus on helping readers understand specifications, compatibility and meaningful product trade-offs.

Covers: Monitors, Graphics cards, Processors, PC components, Peripherals, Upgrades and compatibility

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