Buying Guide
The Best Ergonomic Wireless Mouse
Five mice compared, from the Lenovo WL310 to the MX Vertical, with the trade-offs of each named.
By Alex Morgan, PC Hardware Editor
12 min read5 products evaluated

An ergonomic wireless mouse changes the grip, with a vertical handshake, a thumb trackball or a sculpted shape, and removes the cable drag. These are ordered by listed battery life.
Our comparison rests on published figures for battery life, sensor and grip; where a maker leaves out battery life, we say so, and no figure here comes from our own testing.
Quick Picks
Which of the 5 picks to look at first. Tap a name for the full analysis.

Also Consider
Logitech M720 Triathlon Multi-Device MouseSwitching between 3 computers at the touch of a button.
Best for: Buyers who want switching between 3 computers at the touch of a button.
Check price for Logitech M720 Triathlon Multi-Device Mouse on Amazon (opens in a new tab)
Strong Alternative
Logitech Signature M650Customizable side buttons.
Best for: Buyers who want customizable side buttons.
Check price for Logitech Signature M650 on Amazon (opens in a new tab)
Lowest Price Here
Lenovo WL310 Bluetooth Silent MouseA lower price than the M720 and the rest when we checked.
Best for: Buyers who would rather put the savings elsewhere than into the M720.
Check price for Lenovo WL310 Bluetooth Silent Mouse on Amazon (opens in a new tab)
Worth a Look
Logitech Lift VerticalWhisper-quiet clicks.
Best for: Buyers who want whisper-quiet clicks.
Check price for Logitech Lift Vertical on Amazon (opens in a new tab)
Highest-Resolution Sensor
Logitech MX Vertical Wireless Ergonomic MouseThe highest sensor resolution here (4,000 DPI).
Best for: Users who move the cursor across very wide desktops.
Check price for Logitech MX Vertical Wireless Ergonomic Mouse on Amazon (opens in a new tab)
Our Picks
Also Consider1 of 5
Logitech M720 Triathlon Multi-Device Mouse
Logitech's M720 Triathlon switches between three computers with a button and supports Logitech Flow.
Best for
- Buyers who want switching between 3 computers at the touch of a button.
Skip if
- Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Why we like it
It has 24 months of battery life. Its hyper-fast scroll wheel spins freely through long documents and switches back to click-by-click scrolling when you need precision. The rubber body and sculpted right-hand shape suit a relaxed palm grip.
Logitech Flow moves the cursor, text and files between up to three computers, and it connects over Bluetooth or the Unifying receiver. The Unifying receiver can also pair up to six compatible Logitech devices, which saves USB ports. When we checked, only the Lenovo WL310 cost less, and the Signature M650 cost more. If you want a confirmed sensor resolution, look to the MX Vertical instead: it offers 4,000 DPI, while this one gives no figure.
Key specs
- Battery life
- up to 24 months
- Programmable buttons
- 6
- Grip
- Full-size, right-handed
- Connection
- Bluetooth or Unifying receiver, 3 devices
Pros
- Switching between 3 computers at the touch of a button
- Logitech Flow across computers
- Unifying receiver for up to 6 Logitech devices
Cons
- Costs more than the Lenovo WL310 at the time of writing
Strong Alternative2 of 5
Logitech Signature M650
Logitech's Signature M650 is a quiet-click mouse sized for small to medium hands.
Best for
- Buyers who want customizable side buttons.
Skip if
- Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Why we like it
It supports Windows, macOS, Linux, ChromeOS, iPadOS and Android. Its SmartWheel switches between line-by-line and fast scrolling, and rubber grips suit small to medium hands. Plastics include up to 64% recycled material.
It shares a bluetooth or Logi Bolt connection with the Lift; the Lenovo WL310 goes with a bluetooth 5.0 connection. It also offers customizable side buttons and silent clicks. It is shaped for right hands only.
It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. When we checked, only the M720 and cheaper picks cost less, and the Lift cost more. If you want a confirmed sensor resolution, look to the MX Vertical instead: it offers 4,000 DPI, while this one gives no figure.
Key specs
- Battery life
- up to 24 months
- Grip
- Right-handed, small to medium hands
- Connection
- Bluetooth or Logi Bolt
Pros
- Customizable side buttons
- Silent clicks
- Support for Windows, macOS, Linux, ChromeOS, iPadOS and Android
Cons
- Costs more than the Lenovo WL310 at the time of writing
Lowest Price Here3 of 5
Lenovo WL310 Bluetooth Silent Mouse
Lenovo's WL310 is a silent Bluetooth mouse with 1000, 1200 and 1600 DPI steps.
Best for
- Buyers who would rather put the savings elsewhere than into the M720.
Skip if
- Choose another pick if you can't accept this: sensor resolution of 1,600 DPI, behind the MX Vertical (4,000 DPI).
Why we like it
It needs no receiver. Its clicks are near silent, which suits shared rooms and late sessions. DPI switches between 1,000, 1,200 and 1,600.
You get a bluetooth 5.0 connection here, which sets it apart from the Lift and its a bluetooth or Logi Bolt connection. Another plus: ergonomic grip, the only one here. It makes the most sense for buyers who would rather put the savings elsewhere than into the M720, since it offers a lower price than the M720 and the rest when we checked.
It cost the least of the 5 picks at the time of writing, with the M720 the next step up. There is no published battery life figure, whereas the M720 runs for up to 24 months.
Key specs
- Sensor
- 1,600 DPI
- Grip
- Ergonomic
- Connection
- Bluetooth 5.0
Pros
- Silent clicks
- 1000, 1200 and 1600 DPI steps
- No USB receiver needed
- Ergonomic grip, the only one here
Cons
- Sensor resolution of 1,600 DPI, behind the MX Vertical (4,000 DPI)
Worth a Look4 of 5
Logitech Lift Vertical
Lift is Logitech's vertical mouse for small to medium right hands, holding the wrist at 57 degrees to reduce forearm twist.
Best for
- Buyers who want whisper-quiet clicks.
Skip if
- If budget leads, the Lenovo WL310 was cheaper at our last price check.
Why we like it
It adds whisper-quiet clicks and a SmartWheel, and connects over Bluetooth or Logi Bolt. Logitech sizes it for small to medium right hands, with a 57-degree angle and a padded thumb rest. The soft-textured grip suits all-day office use.
The plastic parts include certified post-consumer recycled plastic, and it works with Windows, macOS, iPadOS, Chrome OS and Linux. It shares a bluetooth or Logi Bolt connection with the Signature M650; the Lenovo WL310 goes with a bluetooth 5.0 connection. You also get certification by leading ergonomists.
Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. When we checked, only the Signature M650 and cheaper picks cost less, and the MX Vertical cost more.
Key specs
- Grip
- 57-degree vertical, right-handed, small to medium hands
- Connection
- Bluetooth or Logi Bolt
Pros
- Whisper-quiet clicks
- Certification by leading ergonomists
- Bluetooth or Logi Bolt connection
Cons
- Costs more than the Lenovo WL310 at the time of writing
The catch
If you want a confirmed battery life, look to the M720 instead: it runs for up to 24 months, while this one gives no figure.
Highest-Resolution Sensor5 of 5
Logitech MX Vertical Wireless Ergonomic Mouse
Logitech's MX Vertical sets the hand at 57 degrees with a thumb rest and a textured rubber surface.
Best for
- Users who move the cursor across very wide desktops.
Skip if
- Skip it if price comes first: the Lenovo WL310 cost less when we checked.
Why we like it
A cursor speed switch changes sensitivity with one press, and Logitech says the shape fits a variety of hand sizes. Its 57-degree angle puts your hand in a handshake position, which Logitech says reduces muscle activity by 10%. The design was tested against criteria from ergonomists.
Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It is shaped for right hands only. Only the Lift came close to it on price at the time of writing; it cost the most of the 5 picks. There is no published battery life figure, whereas the M720 runs for up to 24 months.
Key specs
- Sensor
- 4,000 DPI
- Grip
- Vertical, right-handed (57°)
- Connection
- Wireless, USB receiver
Pros
- 57-degree vertical angle with a thumb rest
- Cursor speed switch that changes DPI with one button
- Textured rubber surface
- Highest sensor resolution of the picks (4,000 DPI)
Cons
- Costs more than the Lenovo WL310 at the time of writing
How We Chose
Alex Morgan compared the manufacturer specifications, connectivity, warranty terms and compatibility of every pick. Figures come from the makers unless a third-party source is named; we did not test these products ourselves.

- How these picks were ranked
- We lined up five mice on battery life, sensor resolution, grip and connection, using each maker's published specs. These are research figures, not bench results: 3 of 5 picks leave out battery life.
- The shared baseline
- All 5, from the M720 to the MX Vertical, state grip and connection.
- Where the specs have gaps
- The Lenovo WL310, the Lift and the MX Vertical give no battery life; the M720, the Signature M650 and the Lift give no sensor resolution.
- Price range
- At our last check the picks ran from the Lenovo WL310 (under $50) to the MX Vertical ($50 to $100).
What to Look for in an Ergonomic Wireless Mouse
Key buying criteria so you get the right fit the first time.
Sensor resolution across these picks
Here sensor resolution runs from 1,600 DPI on the Lenovo WL310 to 4,000 DPI on the MX Vertical, a 150% spread. Start with the MX Vertical if sensor resolution decides it. The M720, the Signature M650 and the Lift give no sensor resolution figure, so 2 of 5 picks are compared here.
Features beyond the spec table
The Lenovo WL310: 1000, 1200 and 1600 DPI steps. The Lift: certification by leading ergonomists. The MX Vertical: a cursor speed switch that changes DPI with one button.

A hand next to a black wireless mouse on a blue mousepad Budget
Under $50 buys the Lenovo WL310, the M720 and the Signature M650; $50 to $100 buys the Lift and the MX Vertical at our last check.
Match the pick to your priority
Buyers who would rather put the savings elsewhere than into the M720: the Lenovo WL310. Users who move the cursor across very wide desktops: the MX Vertical.

A hand holding a light-blue mouse on a red mousepad Quiet clicks for shared rooms
Silent or quiet-click switches reduce noise on calls and in shared offices. The feel is slightly softer.
How to Choose an Ergonomic Wireless Mouse
By priority
| Priority | Consider | Why |
|---|---|---|
| Buyers who want switching between 3 computers at the touch of a button | M720 | Switching between 3 computers at the touch of a button |
| Buyers who want customizable side buttons | Signature M650 | Customizable side buttons |
| Buyers who would rather put the savings elsewhere than into the M720 | Lenovo WL310 | A lower price than the M720 and the rest when we checked |
| Buyers who want whisper-quiet clicks | Lift | Whisper-quiet clicks |
| Users who move the cursor across very wide desktops | MX Vertical | The highest sensor resolution here (4,000 DPI) |
Scroll sideways to see every column.
Key specs side by side
The MX Vertical leads on sensor resolution at 4,000 DPI, ahead of the Lenovo WL310 at 1,600 DPI. "Not listed" marks battery life where the Lenovo WL310, the Lift and the MX Vertical leave the figure out.
| Mice | Battery life | Sensor | Grip | Connection |
|---|---|---|---|---|
| M720 | up to 24 months | Not listed | Full-size, right-handed | Bluetooth or Unifying receiver, 3 devices |
| Signature M650 | up to 24 months | Not listed | Right-handed, small to medium hands | Bluetooth or Logi Bolt |
| Lenovo WL310 | Not listed | 1,600 DPI | Ergonomic | Bluetooth 5.0 |
| Lift | Not listed | Not listed | 57-degree vertical, right-handed, small to medium hands | Bluetooth or Logi Bolt |
| MX Vertical | Not listed | 4,000 DPI | Vertical, right-handed (57°) | Wireless, USB receiver |
Scroll sideways to see every column.
By price at the time of writing
At our last check the cheapest pick, the Lenovo WL310, sat in the under $50 tier, 2 tiers in all up to the MX Vertical at $50 to $100; Amazon prices move, so recheck before buying.
| Price tier | Mice |
|---|---|
| Under $50 | Lenovo WL310, M720, Signature M650 |
| About $50 to $100 | Lift, MX Vertical |
Frequently Asked Questions
How does the Lenovo WL310 compare with the MX Vertical on sensor resolution?
Between the top two, it is 4,000 DPI on the MX Vertical against 1,600 DPI on the Lenovo WL310, a 150% difference. No sensor resolution figure is published for the M720, the Signature M650 and the Lift, which leaves 2 of 5 picks ranked here.
Is the MX Vertical worth paying more than the Lenovo WL310?
On paper it adds sensor resolution (4,000 DPI against 1,600 DPI). The Lenovo WL310 sat in the under $50 tier and the MX Vertical in the $50 to $100 tier when we checked, with 3 other picks between them; pay the difference only if sensor resolution decides your purchase.
What makes the MX Vertical the Highest-Resolution Sensor?
The label rests on the highest sensor resolution here (4,000 DPI). The Lenovo WL310 is next on sensor resolution at 1,600 DPI, so this pick's 4,000 DPI is 150% further out. The Lenovo WL310, the cheapest pick, sat in the under $50 tier against $50 to $100 here, without out-ranking it on any listed spec. It is aimed at anyone who moves the cursor across very wide desktops.
Beyond the specs, what sets the M720 and the Signature M650 apart?
The M720: switching between 3 computers at the touch of a button. The Signature M650: customizable side buttons. The Lenovo WL310: silent clicks.
Should I pick the M720 or the MX Vertical?
The M720 suits buyers who want switching between 3 computers at the touch of a button; the MX Vertical suits users who move the cursor across very wide desktops.
Bottom Line
Our first pick is the M720, chosen for switching between 3 computers at the touch of a button. Look at the Signature M650 for customizable side buttons, the Lenovo WL310 for a lower price than the M720 and the rest when we checked and the Lift for whisper-quiet clicks if those matter more to you.
Any new grip takes a week or so to adjust to; give it time before judging.
Related Guides
- Related guideThe Best Mice for Work
- Related guideThe Best Bluetooth Wireless Mice
- Related guideThe Best Vertical Ergonomic Mice
- Lower budgetThe Best Mice Under $150
- Similar guideThe Best Wireless Mouse
- ExplainerHow to Choose a Gaming Mouse
- ExplainerMouse polling rate and DPI: what each number changes
- Also see: mouse pads and desk matsMouse Pad Features Explained: What Is Worth Paying For?
- Similar guideThe Best Razer Wireless Mice
- Topic hubAll mice guides
About the author
PC Hardware Editor
Alex covers PC hardware, monitors, components, upgrades and peripherals for The PC Journal, with a focus on helping readers understand specifications, compatibility and meaningful product trade-offs.
Covers: Monitors, Graphics cards, Processors, PC components, Peripherals, Upgrades and compatibility
View all articles