Buying Guide

The Best Vertical Ergonomic Mice

Six vertical mice that turn the hand to a handshake position, including a left-handed Logitech and a wired Anker under $20.

By , PC Hardware Editor

12 min read6 products evaluated

A desk setup with a keyboard, mouse and headset beside a monitor
Illustrative image

A vertical mouse turns your hand to a handshake position instead of palm-down, which reduces forearm twist for people who feel strain from a flat mouse. Expect a week or so to adjust. The biggest mistake is buying the wrong size, so check the hand-size guidance each maker gives.

We researched six vertical mice from their Amazon listings and makers' specifications. We did not test them, and we make no medical claims; if you have pain, a clinician is the right person to advise on it.

Quick Picks

Which of the 6 picks to look at first. Tap a name for the full analysis.

  1. Best Cursor Control

    Logitech MX Vertical Wireless Ergonomic Mouse

    A cursor speed switch that changes DPI with one press, on a 57-degree shape.

    Best for: Right-handed users who switch between detail work and big screens.

    Check price for Logitech MX Vertical Wireless Ergonomic Mouse on Amazon (opens in a new tab)
  2. Best for Smaller Hands

    Logitech Lift Vertical Ergonomic Wireless Mouse

    A shape Logitech sizes for small to medium right hands, with whisper-quiet clicks.

    Best for: Small to medium hands in shared offices.

    Check price for Logitech Lift Vertical Ergonomic Wireless Mouse on Amazon (opens in a new tab)
  3. Best Left-Handed

    Logitech Lift Left Vertical Ergonomic Wireless Mouse

    A left-handed version of the Lift with the thumb rest mirrored.

    Best for: Left-handed users, who have few vertical options.

    Check price for Logitech Lift Left Vertical Ergonomic Wireless Mouse on Amazon (opens in a new tab)
  4. Highest-Resolution Sensor

    Razer Pro Click V2 Vertical Wireless Mouse

    The highest sensor resolution here (30,000 DPI).

    Best for: Users who move the cursor across very wide desktops.

    Check price for Razer Pro Click V2 Vertical Wireless Mouse on Amazon (opens in a new tab)
  5. Best Budget Rechargeable

    ProtoArc EM11 NL Wireless Ergonomic Vertical Mouse

    A USB-C rechargeable battery and silent main buttons under $30 at the time of writing.

    Best for: Hands under 7.5 inches on a budget.

    Check price for ProtoArc EM11 NL Wireless Ergonomic Vertical Mouse on Amazon (opens in a new tab)
  6. Best Wired Option

    Anker Wired Vertical Ergonomic Mouse

    A wired USB connection with nothing to charge.

    Best for: Trying a vertical grip for the least money.

    Check price for Anker Wired Vertical Ergonomic Mouse on Amazon (opens in a new tab)

Our Picks

Best Cursor Control1 of 6

Logitech MX Vertical Wireless Ergonomic Mouse

Logitech's MX Vertical sets the hand at 57 degrees with a thumb rest and a textured rubber surface.

Best for

Right-handed users who switch between detail work and big screens.

Skip if

Skip it if you need to know its battery life before buying; the maker doesn't publish one.
Logitech MX Vertical Wireless Ergonomic Mouse

Why we like it

A cursor speed switch changes sensitivity with one press, and Logitech says the shape fits a variety of hand sizes. Its 57-degree angle puts your hand in a handshake position, which Logitech says reduces muscle activity by 10%. The design was tested against criteria from ergonomists.

Its 4,000 DPI sensor resolution ranks second of 4 here, behind the Pro Click V2 Vertical (30,000 DPI) and ahead of the Anker wired vertical (1,600 DPI). Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It is shaped for right hands only. When we checked, only the Lift and cheaper picks cost less, and the Lift Left cost more.

Key specs

Sensor
4,000 DPI
Grip
Vertical, right-handed (57°)
Connection
Wireless, USB receiver

Pros

  • 57-degree vertical angle with a thumb rest
  • Cursor speed switch that changes DPI with one button
  • Textured rubber surface
  • Sensor resolution of 4,000 DPI, ahead of the EM11 NL

Cons

  • No published battery life
  • Costs more than the Anker wired vertical at the time of writing

The catch

If you want a confirmed battery life, look to the Lift instead: it runs for up to 24 months, while this one gives no figure.

Best for Smaller Hands2 of 6

Logitech Lift Vertical Ergonomic Wireless Mouse

Logitech's Lift is a smaller vertical mouse sized for small to medium right hands, with whisper-quiet clicks and a SmartWheel.

Best for

Small to medium hands in shared offices.

Skip if

Pass if a published sensor resolution matters; this one has none.
Logitech Lift Vertical Ergonomic Wireless Mouse

Why we like it

It connects over Bluetooth LE or a Logi Bolt receiver and Logitech offers up to two years of battery life. Logitech sizes it for small to medium right hands, with a 57-degree angle and a padded thumb rest. The soft-textured grip suits all-day office use.

The plastic parts include certified post-consumer recycled plastic, and it works with Windows, macOS, iPadOS, Chrome OS and Linux. It matches the Lift Left on battery life (up to 24 months). You also get a SmartWheel for fast or line-by-line scrolling and customizable buttons within thumb reach.

Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. It was priced above the EM11 NL and below the MX Vertical at the time of writing.

Key specs

Battery life
up to 24 months
Grip
Vertical, right-handed, small to medium hands (57°)
Connection
Bluetooth LE or Logi Bolt USB receiver

Pros

  • Whisper-quiet clicks
  • SmartWheel for fast or line-by-line scrolling
  • Customizable buttons within thumb reach
  • Battery life of up to 24 months, ahead of the Pro Click V2 Vertical

Cons

  • No published sensor resolution
  • Costs more than the Anker wired vertical at the time of writing

The catch

There is no published sensor resolution figure, whereas the Pro Click V2 Vertical offers 30,000 DPI.

Best Left-Handed3 of 6

Logitech Lift Left Vertical Ergonomic Wireless Mouse

The Lift Left mirrors Logitech's Lift for the left hand, with the thumb rest sculpted on the other side.

Best for

Left-handed users, who have few vertical options.

Skip if

Pass if a published sensor resolution matters; this one has none.
Logitech Lift Left Vertical Ergonomic Wireless Mouse

Why we like it

The quiet clicks, SmartWheel and two-year battery rating are the same. This is the left-handed version of Logitech's Lift, sized for small to medium hands. It keeps the 57-degree angle and adds a thumb rest shaped for the left hand.

It matches the Lift on battery life (up to 24 months). You also get a SmartWheel for fast or line-by-line scrolling. Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size.

It connects over Bluetooth or a Logi Bolt receiver; Bolt does not pair with older Unifying receivers. It was priced above the MX Vertical and below the Pro Click V2 Vertical at the time of writing.

Key specs

Battery life
up to 24 months
Grip
Vertical, left-handed, small to medium hands (57°)
Connection
Bluetooth LE or Logi Bolt USB receiver

Pros

  • Thumb rest sculpted for left hands
  • Whisper-quiet clicks
  • SmartWheel for fast or line-by-line scrolling
  • Battery life of up to 24 months, ahead of the Pro Click V2 Vertical

Cons

  • No published sensor resolution
  • Costs more than the Anker wired vertical at the time of writing

The catch

There is no published sensor resolution figure, whereas the Pro Click V2 Vertical offers 30,000 DPI.

Highest-Resolution Sensor4 of 6

Razer Pro Click V2 Vertical Wireless Mouse

Razer's Pro Click V2 Vertical adds a base support that raises the wrist off the desk, plus six buttons and 18-zone lighting.

Best for

Users who move the cursor across very wide desktops.

Skip if

Skip it if battery life matters most to you; the Lift offers up to 24 months.
Razer Pro Click V2 Vertical Wireless Mouse

Why we like it

It connects to up to five devices over HyperSpeed, Bluetooth or cable, and a 5-minute charge gives three working days. On battery life it trails the group at up to 6 months, while the Lift runs for up to 24 months. Its 30,000 DPI sensor resolution is the highest here; the MX Vertical comes next at 4,000 DPI.

You also get a Focus Pro 30K sensor that tracks on glass. Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It is shaped for right hands only. It was the highest-priced of the 6 picks at the time of writing, so the case for it rests on what it adds over the Lift Left and the rest.

Key specs

Battery life
up to 6 months
Sensor
30,000 DPI
Programmable buttons
6
Grip
Vertical, right-handed, with base support
Connection
HyperSpeed 2.4GHz, Bluetooth or wired, up to 5 devices

Pros

  • Base support that raises the wrist off the desk
  • 3 working days of use from a 5-minute charge
  • Focus Pro 30K sensor that tracks on glass
  • Highest sensor resolution of the picks (30,000 DPI)

Cons

  • Battery life trails the Lift (up to 24 months)
  • Costs more than the Anker wired vertical at the time of writing

The catch

The trade-off is battery life; for more, the Lift runs for up to 24 months.

Best Budget Rechargeable5 of 6

ProtoArc EM11 NL Wireless Ergonomic Vertical Mouse

ProtoArc's EM11 NL is a 58-degree vertical mouse for hands under 7.5 inches, with silent left and right buttons.

Best for

Hands under 7.5 inches on a budget.

Skip if

The maker gives no battery life, so skip it if that figure decides your choice.
ProtoArc EM11 NL Wireless Ergonomic Vertical Mouse

Why we like it

It recharges over USB-C and pairs with three devices across two Bluetooth channels and a 2.4GHz receiver. It charges in about 2 hours over the included Type-C cable and lists up to 200 days of standby. The scroll wheel and the back and forward buttons are not silent.

On sensor resolution it sits mid-pack at 2,400 DPI: the Pro Click V2 Vertical offers 30,000 DPI, and the Anker wired vertical comes in at 1,600 DPI. You also get a USB-C rechargeable 500mAh battery rated for up to 100 hours and a stated hand-length limit of 7.5 inches. Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. Its price falls between the Anker wired vertical and the Lift, based on our last check.

Key specs

Sensor
2,400 DPI
Grip
Vertical, right-handed, hands under 7.5 in (58°)
Connection
Bluetooth (2 channels) and 2.4GHz, 3 devices

Pros

  • Silent left and right buttons (the wheel and side buttons are not silent)
  • USB-C rechargeable 500mAh battery rated for up to 100 hours
  • Stated hand-length limit of 7.5 inches
  • Sensor resolution of 2,400 DPI, ahead of the Anker wired vertical

Cons

  • No published battery life
  • Costs more than the Anker wired vertical at the time of writing

The catch

Buyers who need a confirmed battery life should compare it with the Lift, which runs for up to 24 months.

Best Wired Option6 of 6

Anker Wired Vertical Ergonomic Mouse

Anker's wired vertical mouse is the simplest way to try the handshake grip: a 5.3oz body on a 1.5m USB cable with nothing to charge.

Best for

Trying a vertical grip for the least money.

Skip if

Skip it if sensor resolution matters most to you; the Pro Click V2 Vertical offers 30,000 DPI.
Anker Wired Vertical Ergonomic Mouse

Why we like it

It has next and previous page buttons and an 18-month warranty. Its handshake position eases wrist strain, and at 5.3 oz it is light. DPI switches between 1,000 and 1,600.

Its vertical shape holds the hand in a handshake position. DPI switches between 1000 and 1600, and next and previous buttons handle web browsing. Its 1,600 DPI sensor resolution is the lowest in this group; the Pro Click V2 Vertical leads at 30,000 DPI.

Vertical mice put your hand in a handshake position; allow a week to adjust, and check the hand size. It is shaped for right hands only. It cost the least of the 6 picks at the time of writing, with the EM11 NL the next step up.

Key specs

Sensor
1,600 DPI
Grip
Vertical, right-handed
Connection
Wired USB, 1.5m cable

Pros

  • 5.3oz body
  • 18-month warranty
  • Next and previous page buttons
  • A wired USB connection with nothing to charge

Cons

  • Sensor resolution trails the Pro Click V2 Vertical (30,000 DPI)

The catch

There is no published battery life figure, whereas the Lift runs for up to 24 months.

How We Chose These Vertical Ergonomic Mice

Alex Morgan compared the manufacturer specifications, connectivity, warranty terms and compatibility of every pick. Figures come from the makers unless a third-party source is named; we did not test these products ourselves.

A hand next to a black wireless mouse on a blue mousepad
A hand next to a black wireless mouse on a blue mousepad
What we compared
We lined up six mice on battery life, sensor resolution, grip and connection from manufacturer specifications. We did not test them in-house, and battery life and sensor resolution are missing for at least one pick.
The shared baseline
All 6, from the MX Vertical to the Anker wired vertical, state grip and connection.
Where the specs have gaps
The MX Vertical, the EM11 NL and the Anker wired vertical give no battery life; the Lift and the Lift Left give no sensor resolution.
Price range
At our last check the picks ran from the Anker wired vertical (under $50) to the Pro Click V2 Vertical ($50 to $100).

What to Look for in a Vertical Ergonomic Mouse

Key buying criteria so you get the right fit the first time.

  1. Sensor resolution across these picks

    Across these 4 picks sensor resolution spans 1,600 DPI (the Anker wired vertical) to 30,000 DPI (the Pro Click V2 Vertical). For less, the MX Vertical is the runner-up at 4,000 DPI. The Lift and the Lift Left give no sensor resolution figure, so 4 of 6 picks are compared here.

  2. Battery life

    Here battery life runs from up to 6 months on the Pro Click V2 Vertical to up to 24 months on the Lift, a 300% spread. Start with the Lift if battery life decides it. The MX Vertical, the EM11 NL and the Anker wired vertical give no battery life figure, so 3 of 6 picks are compared here.

    A hand holding a light-blue mouse on a red mousepad
    A hand holding a light-blue mouse on a red mousepad
  3. Features beyond the spec table

    The Pro Click V2 Vertical: 3 working days of use from a 5-minute charge. The EM11 NL: a USB-C rechargeable 500mAh battery rated for up to 100 hours. The Anker wired vertical: an 18-month warranty.

  4. How much to spend

    Under $50 buys the Anker wired vertical and the EM11 NL; $50 to $100 buys the Lift, the MX Vertical, the Lift Left and the Pro Click V2 Vertical at our last check.

    A hand on a white gaming mouse, and the same mouse shown from below
    A hand on a white gaming mouse, and the same mouse shown from below
  5. Match the pick to your priority

    Right-handed users who switch between detail work and big screens: the MX Vertical. Small to medium hands in shared offices: the Lift. Left-handed users, who have few vertical options: the Lift Left.

How to Choose a Vertical Ergonomic Mouse

By priority

PriorityConsiderWhy
Right-handed users who switch between detail work and big screensMX VerticalA cursor speed switch that changes DPI with one press, on a 57-degree shape
Small to medium hands in shared officesLiftA shape Logitech sizes for small to medium right hands, with whisper-quiet clicks
Left-handed users, who have few vertical optionsLift LeftA left-handed version of the Lift with the thumb rest mirrored
Users who move the cursor across very wide desktopsPro Click V2 VerticalThe highest sensor resolution here (30,000 DPI)
Hands under 7.5 inches on a budgetEM11 NLA USB-C rechargeable battery and silent main buttons under $30 at the time of writing
Trying a vertical grip for the least moneyAnker wired verticalA wired USB connection with nothing to charge

Scroll sideways to see every column.

Key specs side by side

The Pro Click V2 Vertical leads on sensor resolution at 30,000 DPI, ahead of the MX Vertical at 4,000 DPI. "Not listed" marks battery life where the MX Vertical, the EM11 NL and the Anker wired vertical leave the figure out.

MiceBattery lifeSensorGripConnection
MX VerticalNot listed4,000 DPIVertical, right-handed (57°)Wireless, USB receiver
Liftup to 24 monthsNot listedVertical, right-handed, small to medium hands (57°)Bluetooth LE or Logi Bolt USB receiver
Lift Leftup to 24 monthsNot listedVertical, left-handed, small to medium hands (57°)Bluetooth LE or Logi Bolt USB receiver
Pro Click V2 Verticalup to 6 months30,000 DPIVertical, right-handed, with base supportHyperSpeed 2.4GHz, Bluetooth or wired, up to 5 devices
EM11 NLNot listed2,400 DPIVertical, right-handed, hands under 7.5 in (58°)Bluetooth (2 channels) and 2.4GHz, 3 devices
Anker wired verticalNot listed1,600 DPIVertical, right-handedWired USB, 1.5m cable

Scroll sideways to see every column.

By price at the time of writing

At our last check the cheapest pick, the Anker wired vertical, sat in the under $50 tier, 2 tiers in all up to the Pro Click V2 Vertical at $50 to $100; Amazon prices move, so recheck before buying.

Price tierMice
Under $50Anker wired vertical, EM11 NL
About $50 to $100Lift, MX Vertical, Lift Left, Pro Click V2 Vertical

Frequently Asked Questions

How does the MX Vertical compare with the Pro Click V2 Vertical on sensor resolution?

Between the top two, it is 30,000 DPI on the Pro Click V2 Vertical against 4,000 DPI on the MX Vertical, a 650% difference. The Anker wired vertical closes the ranking at 1,600 DPI. The Lift and the Lift Left don't state a sensor resolution figure, so they sit outside this comparison; 4 of 6 picks are ranked.

Is the Pro Click V2 Vertical worth paying more than the Anker wired vertical?

On paper it adds sensor resolution (30,000 DPI against 1,600 DPI). The Anker wired vertical sat in the under $50 tier and the Pro Click V2 Vertical in the $50 to $100 tier when we checked, with 4 other picks between them; pay the difference only if sensor resolution decides your purchase.

What makes the Lift Left the Best Left-Handed?

It carries the badge for a left-handed version of the Lift with the thumb rest mirrored. The Anker wired vertical, the cheapest pick, sat in the under $50 tier against $50 to $100 here, without out-ranking it on any listed spec. It is aimed at left-handed users, who have few vertical options.

Beyond the specs, what sets the MX Vertical and the Lift apart?

The MX Vertical: a 57-degree vertical angle with a thumb rest. The Lift: whisper-quiet clicks. The Lift Left: a thumb rest sculpted for left hands.

Who should choose the MX Vertical?

The MX Vertical carries our Best Cursor Control label for a cursor speed switch that changes DPI with one press, on a 57-degree shape. It ranks first of 6 here and sat in the $50 to $100 tier at our last price check; it suits right-handed users who switch between detail work and big screens.

Bottom Line

The Logitech MX Vertical is the pick for one-press cursor speed changes on a 57-degree shape, while the Logitech Lift is the smaller, quieter option Logitech sizes for small to medium hands, and the Lift Left is the rare left-handed model.

The Razer Pro Click V2 Vertical adds a wrist base, six buttons and five-device switching. The ProtoArc EM11 NL is the budget rechargeable pick for hands under 7.5 inches, and the Anker wired vertical mouse is the cheapest way to find out whether the grip works for you.

About the author

PC Hardware Editor

Alex covers PC hardware, monitors, components, upgrades and peripherals for The PC Journal, with a focus on helping readers understand specifications, compatibility and meaningful product trade-offs.

Covers: Monitors, Graphics cards, Processors, PC components, Peripherals, Upgrades and compatibility

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